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Figure 4 | Virology Journal

Figure 4

From: An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice

Figure 4

VLP and cVLP structures formation. Crude extracts of tomato fruit were processed as described in the text and negatively-stained with 2% phosphotungstic acid for 5 min. The samples were imaged on a Philips Morgagni 268 transmission electron microscope. The arrows indicate the putative VLPs observed. (A) Commercial vaccine Gardasil® as control. (B) Transgenic lines with L1. (C) Transgenic lines with L1-E6/E7. (D) non-transformed plant. Bars indicate 0.1 μm.

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