Table 1 Analysis of human influenza virus NEG8 ORFs, post 1950, which vary from the 216 codon length

261

2 (.12%)

Loss of stop codon from 216 codon ORF; ORF runs to end of sequence

258

1 (.06%)

Loss of stop codon from 216 Codon ORF; ORF runs to end of sequence

246

4 (.23%)

Loss of stop codon from 216 Codon ORF.

235

1 (.06%)

Loss of stop codon before 216 ORF start codon; extends 5' end of ORF.

204

1 (.06%)

Mutation resulting in new stop codon.

197

22 (1.3%)

Mutation resulting in new stop codon; not 22 separate events.¹

178

1 (.06%)

Mutation resulting in new stop codon.

167

2 (.12%)

Most closely related to viruses isolated in 1930s; contamination resulting in mis-named viruses.

147

2 (.12%)

Mutation resulting in new stop codon; 2 separate events.

142

20 (1.1%)

Loss of start codon or new stop codon close to start of NEG 8 ORF.²

140

2 (.12%)

Mutation resulting in new stop codon; 1 event.

135

12 (.69%)

Mutation resulting in new stop codon; 4 separate events.

91

1 (.06%)

Mutation resulting in new stop codon.