TY - JOUR AU - Gupta, R. AU - Warren, T. AU - Wald, A. PY - 2007 DA - 2007// TI - Genital herpes JO - Lancet VL - 370 UR - https://doi.org/10.1016/S0140-6736(07)61908-4 DO - 10.1016/S0140-6736(07)61908-4 ID - Gupta2007 ER - TY - JOUR AU - Nahmias, A. J. AU - Lee, F. K. AU - Beckman-Nahmias, S. PY - 1990 DA - 1990// TI - Sero-epidemiological and -sociological patterns of herpes simplex virus infection in the world JO - Scand J Infect Dis Suppl VL - 69 ID - Nahmias1990 ER - TY - JOUR AU - Xu, F. AU - Sternberg, M. R. AU - Kottiri, B. J. AU - McQuillan, G. M. AU - Lee, F. K. AU - Nahmias, A. J. AU - Berman, S. M. AU - Markowitz, L. E. PY - 2006 DA - 2006// TI - Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States JO - Jama VL - 296 UR - https://doi.org/10.1001/jama.296.8.964 DO - 10.1001/jama.296.8.964 ID - Xu2006 ER - TY - JOUR AU - Margolis, T. P. AU - Imai, Y. AU - Yang, L. AU - Vallas, V. AU - Krause, P. R. PY - 2007 DA - 2007// TI - Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts JO - J Virol VL - 81 UR - https://doi.org/10.1128/JVI.02110-06 DO - 10.1128/JVI.02110-06 ID - Margolis2007 ER - TY - JOUR AU - Allsworth, J. E. AU - Lewis, V. A. AU - Peipert, J. F. PY - 2008 DA - 2008// TI - Viral sexually transmitted infections and bacterial vaginosis: 2001-2004 National Health and Nutrition Examination Survey data JO - Sex Transm Dis VL - 35 UR - https://doi.org/10.1097/OLQ.0b013e3181788301 DO - 10.1097/OLQ.0b013e3181788301 ID - Allsworth2008 ER - TY - JOUR AU - Freeman, E. E. AU - Weiss, H. A. AU - Glynn, J. R. AU - Cross, P. L. AU - Whitworth, J. A. AU - Hayes, R. J. PY - 2006 DA - 2006// TI - Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies JO - Aids VL - 20 UR - https://doi.org/10.1097/01.aids.0000198081.09337.a7 DO - 10.1097/01.aids.0000198081.09337.a7 ID - Freeman2006 ER - TY - JOUR AU - Kaul, R. AU - Nagelkerke, N. J. AU - Kimani, J. AU - Ngugi, E. AU - Bwayo, J. J. AU - Macdonald, K. S. AU - Rebbaprgada, A. AU - Fonck, K. AU - Temmerman, M. AU - Ronald, A. R. AU - Moses, S. PY - 2007 DA - 2007// TI - Prevalent herpes simplex virus type 2 infection is associated with altered vaginal flora and an increased susceptibility to multiple sexually transmitted infections JO - J Infect Dis VL - 196 UR - https://doi.org/10.1086/522006 DO - 10.1086/522006 ID - Kaul2007 ER - TY - JOUR AU - Ashley, R. L. AU - Wald, A. PY - 1999 DA - 1999// TI - Genital herpes: review of the epidemic and potential use of type-specific serology JO - Clin Microbiol Rev VL - 12 ID - Ashley1999 ER - TY - JOUR AU - Koelle, D. M. AU - Corey, L. PY - 2008 DA - 2008// TI - Herpes simplex: insights on pathogenesis and possible vaccines JO - Annu Rev Med VL - 59 UR - https://doi.org/10.1146/annurev.med.59.061606.095540 DO - 10.1146/annurev.med.59.061606.095540 ID - Koelle2008 ER - TY - JOUR AU - Fife, K. H. AU - Crumpacker, C. S. AU - Mertz, G. J. AU - Hill, E. L. AU - Boone, G. S. PY - 1994 DA - 1994// TI - Recurrence and resistance patterns of herpes simplex virus following cessation of > or = 6 years of chronic suppression with acyclovir. Acyclovir Study Group JO - J Infect Dis VL - 169 UR - https://doi.org/10.1093/infdis/169.6.1338 DO - 10.1093/infdis/169.6.1338 ID - Fife1994 ER - TY - JOUR AU - Mogensen, T. H. PY - 2009 DA - 2009// TI - Pathogen recognition and inflammatory signaling in innate immune defenses JO - Clin Microbiol Rev VL - 22 UR - https://doi.org/10.1128/CMR.00046-08 DO - 10.1128/CMR.00046-08 ID - Mogensen2009 ER - TY - JOUR AU - Takeuchi, O. AU - Akira, S. PY - 2009 DA - 2009// TI - Innate immunity to virus infection JO - Immunol Rev VL - 227 UR - https://doi.org/10.1111/j.1600-065X.2008.00737.x DO - 10.1111/j.1600-065X.2008.00737.x ID - Takeuchi2009 ER - TY - JOUR AU - Herbst-Kralovetz, M. M. AU - Quayle, A. J. AU - Ficarra, M. AU - Greene, S. AU - Rose, W. A. AU - Chesson, R. AU - Spagnuolo, R. A. AU - Pyles, R. B. PY - 2008 DA - 2008// TI - Quantification and comparison of toll-like receptor expression and responsiveness in primary and immortalized human female lower genital tract epithelia JO - Am J Reprod Immunol VL - 59 UR - https://doi.org/10.1111/j.1600-0897.2007.00566.x DO - 10.1111/j.1600-0897.2007.00566.x ID - Herbst-Kralovetz2008 ER - TY - JOUR AU - Ashkar, A. A. AU - Yao, X. D. AU - Gill, N. AU - Sajic, D. AU - Patrick, A. J. AU - Rosenthal, K. L. PY - 2004 DA - 2004// TI - Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA JO - J Infect Dis VL - 190 UR - https://doi.org/10.1086/425079 DO - 10.1086/425079 ID - Ashkar2004 ER - TY - JOUR AU - Gill, N. AU - Deacon, P. M. AU - Lichty, B. AU - Mossman, K. L. AU - Ashkar, A. A. PY - 2006 DA - 2006// TI - Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production JO - J Virol VL - 80 UR - https://doi.org/10.1128/JVI.01036-06 DO - 10.1128/JVI.01036-06 ID - Gill2006 ER - TY - JOUR AU - Harandi, A. M. AU - Eriksson, K. AU - Holmgren, J. PY - 2003 DA - 2003// TI - A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection JO - J Virol VL - 77 UR - https://doi.org/10.1128/JVI.77.2.953-962.2003 DO - 10.1128/JVI.77.2.953-962.2003 ID - Harandi2003 ER - TY - JOUR AU - Herbst-Kralovetz, M. M. AU - Pyles, R. B. PY - 2006 DA - 2006// TI - Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection JO - J Virol VL - 80 UR - https://doi.org/10.1128/JVI.01099-06 DO - 10.1128/JVI.01099-06 ID - Herbst-Kralovetz2006 ER - TY - JOUR AU - Pyles, R. B. AU - Higgins, D. AU - Chalk, C. AU - Zalar, A. AU - Eiden, J. AU - Brown, C. AU - Van Nest, G. AU - Stanberry, L. R. PY - 2002 DA - 2002// TI - Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection JO - J Virol VL - 76 UR - https://doi.org/10.1128/JVI.76.22.11387-11396.2002 DO - 10.1128/JVI.76.22.11387-11396.2002 ID - Pyles2002 ER - TY - JOUR AU - Svensson, A. AU - Bellner, L. AU - Magnusson, M. AU - Eriksson, K. PY - 2007 DA - 2007// TI - Role of IFN-alpha/beta signaling in the prevention of genital herpes virus type 2 infection JO - J Reprod Immunol VL - 74 UR - https://doi.org/10.1016/j.jri.2006.09.002 DO - 10.1016/j.jri.2006.09.002 ID - Svensson2007 ER - TY - JOUR AU - Ashkar, A. A. AU - Mossman, K. L. AU - Coombes, B. K. AU - Gyles, C. L. AU - Mackenzie, R. PY - 2008 DA - 2008// TI - FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling JO - PLoS Pathog VL - 4 UR - https://doi.org/10.1371/journal.ppat.1000233 DO - 10.1371/journal.ppat.1000233 ID - Ashkar2008 ER - TY - JOUR AU - Nakamura, J. AU - Shibata, K. AU - Hasebe, A. AU - Into, T. AU - Watanabe, T. AU - Ohata, N. PY - 2002 DA - 2002// TI - Signaling pathways induced by lipoproteins derived from Mycoplasma salivarium and a synthetic lipopeptide (FSL-1) in normal human gingival fibroblasts JO - Microbiol Immunol VL - 46 UR - https://doi.org/10.1111/j.1348-0421.2002.tb02680.x DO - 10.1111/j.1348-0421.2002.tb02680.x ID - Nakamura2002 ER - TY - JOUR AU - Okusawa, T. AU - Fujita, M. AU - Nakamura, J. AU - Into, T. AU - Yasuda, M. AU - Yoshimura, A. AU - Hara, Y. AU - Hasebe, A. AU - Golenbock, D. T. AU - Morita, M. AU - Kuroki, Y. AU - Ogawa, T. AU - Shibata, K. PY - 2004 DA - 2004// TI - Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6 JO - Infect Immun VL - 72 UR - https://doi.org/10.1128/IAI.72.3.1657-1665.2004 DO - 10.1128/IAI.72.3.1657-1665.2004 ID - Okusawa2004 ER - TY - JOUR AU - Soboll, G. AU - Schaefer, T. M. AU - Wira, C. R. PY - 2006 DA - 2006// TI - Effect of toll-like receptor (TLR) agonists on TLR and microbicide expression in uterine and vaginal tissues of the mouse JO - Am J Reprod Immunol VL - 55 UR - https://doi.org/10.1111/j.1600-0897.2006.00381.x DO - 10.1111/j.1600-0897.2006.00381.x ID - Soboll2006 ER - TY - JOUR AU - Herbst-Kralovetz, M. AU - Pyles, R. PY - 2006 DA - 2006// TI - Toll-like receptors, innate immunity and HSV pathogenesis JO - Herpes VL - 13 ID - Herbst-Kralovetz2006 ER - TY - JOUR AU - Mae, M. AU - Iyori, M. AU - Yasuda, M. AU - Shamsul, H. M. AU - Kataoka, H. AU - Kiura, K. AU - Hasebe, A. AU - Totsuka, Y. AU - Shibata, K. PY - 2007 DA - 2007// TI - The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through a Toll-like receptor 2-mediated signalling pathway JO - FEMS Immunol Med Microbiol VL - 49 UR - https://doi.org/10.1111/j.1574-695X.2007.00218.x DO - 10.1111/j.1574-695X.2007.00218.x ID - Mae2007 ER - TY - JOUR AU - Milligan, G. N. AU - Bernstein, D. I. PY - 1995 DA - 1995// TI - Generation of humoral immune responses against herpes simplex virus type 2 in the murine female genital tract JO - Virology VL - 206 UR - https://doi.org/10.1016/S0042-6822(95)80038-7 DO - 10.1016/S0042-6822(95)80038-7 ID - Milligan1995 ER - TY - JOUR AU - Rose, W. A. AU - Tuthill, C. AU - Pyles, R. B. PY - 2008 DA - 2008// TI - An immunomodulating dipeptide, SCV-07, is a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) JO - Int J Antimicrob Agents VL - 32 UR - https://doi.org/10.1016/j.ijantimicag.2008.04.010 DO - 10.1016/j.ijantimicag.2008.04.010 ID - Rose2008 ER - TY - JOUR AU - Corey, L. AU - Huang, M. L. AU - Selke, S. AU - Wald, A. PY - 2005 DA - 2005// TI - Differentiation of herpes simplex virus types 1 and 2 in clinical samples by a real-time taqman PCR assay JO - J Med Virol VL - 76 UR - https://doi.org/10.1002/jmv.20365 DO - 10.1002/jmv.20365 ID - Corey2005 ER - TY - JOUR AU - Moscicki, A. B. PY - 2008 DA - 2008// TI - Vaginal microbicides: where are we and where are we going? JO - J Infect Chemother VL - 14 UR - https://doi.org/10.1007/s10156-008-0630-3 DO - 10.1007/s10156-008-0630-3 ID - Moscicki2008 ER - TY - JOUR AU - Fichorova, R. N. PY - 2004 DA - 2004// TI - Guiding the vaginal microbicide trials with biomarkers of inflammation JO - J Acquir Immune Defic Syndr VL - 37 ID - Fichorova2004 ER - TY - JOUR AU - Sacks, S. L. AU - Griffiths, P. D. AU - Corey, L. AU - Cohen, C. AU - Cunningham, A. AU - Dusheiko, G. M. AU - Self, S. AU - Spruance, S. AU - Stanberry, L. R. AU - Wald, A. AU - Whitley, R. J. PY - 2004 DA - 2004// TI - HSV shedding JO - Antiviral Res VL - 63 UR - https://doi.org/10.1016/j.antiviral.2004.06.004 DO - 10.1016/j.antiviral.2004.06.004 ID - Sacks2004 ER - TY - JOUR AU - Sacks, S. L. AU - Griffiths, P. D. AU - Corey, L. AU - Cohen, C. AU - Cunningham, A. AU - Dusheiko, G. M. AU - Self, S. AU - Spruance, S. AU - Stanberry, L. R. AU - Wald, A. AU - Whitley, R. J. PY - 2004 DA - 2004// TI - HSV-2 transmission JO - Antiviral Res VL - 63 UR - https://doi.org/10.1016/j.antiviral.2004.06.005 DO - 10.1016/j.antiviral.2004.06.005 ID - Sacks2004 ER - TY - JOUR AU - Schwartz, E. J. AU - Blower, S. PY - 2005 DA - 2005// TI - Predicting the potential individual- and population-level effects of imperfect herpes simplex virus type 2 vaccines JO - J Infect Dis VL - 191 UR - https://doi.org/10.1086/429299 DO - 10.1086/429299 ID - Schwartz2005 ER - TY - JOUR AU - MasCasullo, V. AU - Fam, E. AU - Keller, M. J. AU - Herold, B. C. PY - 2005 DA - 2005// TI - Role of mucosal immunity in preventing genital herpes infection JO - Viral Immunol VL - 18 UR - https://doi.org/10.1089/vim.2005.18.595 DO - 10.1089/vim.2005.18.595 ID - MasCasullo2005 ER - TY - JOUR AU - Lund, J. AU - Sato, A. AU - Akira, S. AU - Medzhitov, R. AU - Iwasaki, A. PY - 2003 DA - 2003// TI - Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells JO - J Exp Med VL - 198 UR - https://doi.org/10.1084/jem.20030162 DO - 10.1084/jem.20030162 ID - Lund2003 ER - TY - JOUR AU - Alexopoulou, L. AU - Holt, A. C. AU - Medzhitov, R. AU - Flavell, R. A. PY - 2001 DA - 2001// TI - Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 JO - Nature VL - 413 UR - https://doi.org/10.1038/35099560 DO - 10.1038/35099560 ID - Alexopoulou2001 ER - TY - JOUR AU - Heil, F. AU - Hemmi, H. AU - Hochrein, H. AU - Ampenberger, F. AU - Kirschning, C. AU - Akira, S. AU - Lipford, G. AU - Wagner, H. AU - Bauer, S. PY - 2004 DA - 2004// TI - Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8 JO - Science VL - 303 UR - https://doi.org/10.1126/science.1093620 DO - 10.1126/science.1093620 ID - Heil2004 ER - TY - JOUR AU - Natsuka, M. AU - Uehara, A. AU - Yang, S. AU - Echigo, S. AU - Takada, H. PY - 2008 DA - 2008// TI - A polymer-type water-soluble peptidoglycan exhibited both Toll-like receptor 2- and NOD2-agonistic activities, resulting in synergistic activation of human monocytic cells JO - Innate Immun VL - 14 UR - https://doi.org/10.1177/1753425908096518 DO - 10.1177/1753425908096518 ID - Natsuka2008 ER - TY - JOUR AU - Travassos, L. H. AU - Girardin, S. E. AU - Philpott, D. J. AU - Blanot, D. AU - Nahori, M. A. AU - Werts, C. AU - Boneca, I. G. PY - 2004 DA - 2004// TI - Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition JO - EMBO Rep VL - 5 UR - https://doi.org/10.1038/sj.embor.7400248 DO - 10.1038/sj.embor.7400248 ID - Travassos2004 ER - TY - JOUR AU - Harandi, A. M. AU - Svennerholm, B. AU - Holmgren, J. AU - Eriksson, K. PY - 2001 DA - 2001// TI - Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity JO - J Virol VL - 75 UR - https://doi.org/10.1128/JVI.75.14.6705-6709.2001 DO - 10.1128/JVI.75.14.6705-6709.2001 ID - Harandi2001 ER - TY - JOUR AU - Harandi, A. M. AU - Svennerholm, B. AU - Holmgren, J. AU - Eriksson, K. PY - 2001 DA - 2001// TI - Protective vaccination against genital herpes simplex virus type 2 (HSV-2) infection in mice is associated with a rapid induction of local IFN-gamma-dependent RANTES production following a vaginal viral challenge JO - Am J Reprod Immunol VL - 46 UR - https://doi.org/10.1034/j.1600-0897.2001.d01-34.x DO - 10.1034/j.1600-0897.2001.d01-34.x ID - Harandi2001 ER - TY - JOUR AU - Milligan, G. N. AU - Bernstein, D. I. PY - 1997 DA - 1997// TI - Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract JO - Virology VL - 229 UR - https://doi.org/10.1006/viro.1997.8441 DO - 10.1006/viro.1997.8441 ID - Milligan1997 ER - TY - JOUR AU - Nakayama, T. AU - Shirane, J. AU - Hieshima, K. AU - Shibano, M. AU - Watanabe, M. AU - Jin, Z. AU - Nagakubo, D. AU - Saito, T. AU - Shimomura, Y. AU - Yoshie, O. PY - 2006 DA - 2006// TI - Novel antiviral activity of chemokines JO - Virology VL - 350 UR - https://doi.org/10.1016/j.virol.2006.03.004 DO - 10.1016/j.virol.2006.03.004 ID - Nakayama2006 ER - TY - JOUR AU - Parr, M. B. AU - Parr, E. L. PY - 1999 DA - 1999// TI - The role of gamma interferon in immune resistance to vaginal infection by herpes simplex virus type 2 in mice JO - Virology VL - 258 UR - https://doi.org/10.1006/viro.1999.9739 DO - 10.1006/viro.1999.9739 ID - Parr1999 ER - TY - JOUR AU - Weinberg, A. AU - Rasmussen, L. AU - Merigan, T. C. PY - 1986 DA - 1986// TI - Acute genital infection in guinea pigs: effect of recombinant interleukin-2 on herpes simplex virus type 2 JO - J Infect Dis VL - 154 UR - https://doi.org/10.1093/infdis/154.1.134 DO - 10.1093/infdis/154.1.134 ID - Weinberg1986 ER - TY - JOUR AU - Samuel, C. E. PY - 2001 DA - 2001// TI - Antiviral actions of interferons JO - Clin Microbiol Rev VL - 14 UR - https://doi.org/10.1128/CMR.14.4.778-809.2001 DO - 10.1128/CMR.14.4.778-809.2001 ID - Samuel2001 ER - TY - JOUR AU - Harandi, A. M. AU - Svennerholm, B. AU - Holmgren, J. AU - Eriksson, K. PY - 2001 DA - 2001// TI - Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice JO - J Gen Virol VL - 82 UR - https://doi.org/10.1099/0022-1317-82-4-845 DO - 10.1099/0022-1317-82-4-845 ID - Harandi2001 ER - TY - JOUR AU - Lahiri, A. AU - Das, P. AU - Chakravortty, D. PY - 2008 DA - 2008// TI - Engagement of TLR signaling as adjuvant: towards smarter vaccine and beyond JO - Vaccine VL - 26 UR - https://doi.org/10.1016/j.vaccine.2008.09.045 DO - 10.1016/j.vaccine.2008.09.045 ID - Lahiri2008 ER - TY - JOUR AU - Zhang, X. AU - Chentoufi, A. A. AU - Dasgupta, G. AU - Nesburn, A. B. AU - Wu, M. AU - Zhu, X. AU - Carpenter, D. AU - Wechsler, S. L. AU - You, S. AU - BenMohamed, L. PY - 2009 DA - 2009// TI - A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge JO - Mucosal Immunol VL - 2 UR - https://doi.org/10.1038/mi.2008.81 DO - 10.1038/mi.2008.81 ID - Zhang2009 ER -