Figure 5
From: Inhibition of Monkeypox virus replication by RNA interference
MOI-dependent siA6-a inhibition of MPV replication. Transfected MK2 cells with 20 nM of siA6-a were infected with MPV-GFP at MOIs of 0.001, 0.01, 0.1. Viral replication was traced by measuring the fluorescence increase in culture over duration of 7 days PI. Curves in dashed lines and empty markers represent siA6-a treated cells. Curves in solid lines and filled markers are mock transfected. siA6-a remained effective in cells infected with MPV at MOI of 0.01 for 8 days PI.