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Table 1 IC50, CC50 and therapeutic index (TI) values calculated for each compound against live Nipah and Hendra viruses.

From: Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro

  Brilliant Green Gentian Violet Gliotoxin Ribavirin
NiV IC50 (nM) 218 525 149 3,897
HeV IC50(nM) 778 2,679 579 2,241
CellTiter-Glo® CC50(nM) 4,672 5,865 4,896 149,745
alamarBlue® CC50(nM) 861 2,828 1,609 NDa
NiV TI (CellTiter-Glo®) 21.39 11.16 32.81 38.42
NiV TI (alamarBlue®) 3.95 5.39 10.80 NDa
HeV TI (CellTiter-Glo®) 6.00 2.19 8.44 66.82
HeV TI (alamarBlue®) 1.11 1.06 2.78 NDa
  1. a ND = not determined, values are averages of at least 3 independent experiments.