Table 1 IC₅₀, CC₅₀ and therapeutic index (TI) values calculated for each compound against live Nipah and Hendra viruses.

NiV IC₅₀ (nM)

218

525

149

3,897

HeV IC₅₀(nM)

778

2,679

579

2,241

CellTiter-Glo^® CC₅₀(nM)

4,672

5,865

4,896

149,745

alamarBlue^® CC₅₀(nM)

861

2,828

1,609

ND^a

NiV TI (CellTiter-Glo^®)

21.39

11.16

32.81

38.42

NiV TI (alamarBlue^®)

3.95

5.39

10.80

ND^a

HeV TI (CellTiter-Glo^®)

6.00

2.19

8.44

66.82

HeV TI (alamarBlue^®)

1.11

1.06

2.78

ND^a