Figure 1
From: Induction of cell-cell fusion by ectromelia virus is not inhibited by its fusion inhibitory complex
A) Infection with ECTV induces cell-cell fusion. BS-C-1 and HeLa cells were infected with ECTV virus at MOI = 1. 24 hrs post infection cells were fixed and stained for DAPI (blue), actin (red) and ECTV (green). BS-C-1 control (a), BS-C-1 infected with ECTV (b), HeLa control (c), HeLa infected with ECTV (d). Bar = 100 μm. e) Actin tails (green) with ECTV particles (red) at their tips (designated with arrows). Bar = 1 μm. B) Induction of syncytia by ECTV virus is time and infection titer-dependent. BS-C-1 cells were infected at different moi (0.25, 1, 5 and 10). At different time points cells were fixed and visualized by May-Grunwald and Gimsa staining. Bar = 100 μm.