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Table 1 Selection of MARV epitopes

From: Discovery of common marburgvirus protective epitopes in a BALB/c mouse model

Peptide Poola + Peptide from Poolb 15-mer Sequence % CD8 IFNγc 9-mer Peptide Motif Resultsd % CD8 IFNγ e
GP1-13 GP2 FLISLILIQGTKNLP 2.85 ILIQGTKNL 2.83
GP1-14 GP3 ILIQGTKNLPILEIA 5.09 QGTKNLPIL 3.46
GP2-17 GP19 TCYNISVTDPSGKSL 2.34 VTDPSGKSL 1.68
GP2-19 GP21 SGKSLLLDPPTNIRD 2.6 LLLDPPTNI 1.72
GP7-17 GP84 SPPPTPSSTAQHLVY 3.11 TPSSTAQHL 2.93
GP11-13 GP132 GILLLLSIAVLIALS 8.36 LLLSIAVLI 8.94
GP11-14 GP133 LSIAVLIALSCICRI 2.96 LSIAVLIAL 1.18
GP11-15 GP134 LIALSCICRIFTKYI 2.73 IALSCICRI 4.12
NP1-20 NP144 AINSGIDLGDLLEGG 2.88 NSGIDLGDL 4.13
NP2-13 NP150 KFNTSPVAKYLRDAG 2.53 NTSPVAKYL 4.71
NP2-20 NP157 EPHYSPLILALKTLE 3.48 HYSPLILAL 2.79
VP6-12 VP44 QHKNPNNGPLLAISG 3.17 KNPNNGPLL 2.38
  1. *Tested in adoptive transfer studies
  2. aPools of peptides were each number represents a new 15-mer peptide
  3. bSelected 15-mer peptides capable of restimulating splenocytes of MARV-infected mice
  4. cMean IFNγ levels from two experiments minus mean background
  5. d9 mers derived from HLA binding predictions