Figure 2
From: Discovery of common marburgvirus protective epitopes in a BALB/c mouse model
9-mer peptides, derived from the original 15-mer peptides based on HLA binding predictions, were used to stimulate MARV-specific splenocytes. IFNγ levels were measured in gated CD8+ T-cell populations with high CD44 surface expression. Each 9-mer stimulated CD8+ T cells to produce varying amounts of IFNγ; whereas, the negative control (EBOV NP12) stimulated splenocytes produced minimal IFNγ.