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Table 1 Virus replication levels in hamster lungs

From: Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo

  Virus replication (mean* of N animals) T-test*
  rSCV
(Virus titer, RNA concentration, N animals)
r7bΔTMD
(Virus titer, RNA concentration, N animals)
p
Day 1 p.i. 1.04 × 107 (9.00 × 106 - 1.2 × 107) PFU/g 9.86 × 108 (2.4 × 107 - 1.8 × 108) PFU/g 0.15
  6.65 × 107 ( 1.84 × 107 - 2.4 × 108) copies/g 1.53 × 109 (9.98 × 108 - 2.2 × 109) copies/g 0.052
  n = 2 n = 3  
Day 3 p.i. 9.86 × 106 (8.00 × 105 - 1.20 × 108) PFU/g 1.63 × 108 (1.00 × 108 - 3.6 × 108) PFU/g 0.13
  4.27 × 108 (1.68 × 108 - 2.1 × 109) copies/g 7.70E × 108 (7.50 × 108 - 8.10 × 108) copies/g 0.5
  n = 3 n = 3  
  1. * Means were determined upon logarithmic data and calculated back into linear values. Two-tailed t-tests were done on logarithmic values