Figure 6From: 9-aminoacridine Inhibition of HIV-1 Tat Dependent Transcription9AA treatment results in loss of cdk9 from the HIV-1 LTR. ACH2 cells were treated with either DMSO or 2.5 μM 9AA for 48 hours, cross-linked and collected for ChIP analysis. Antibodies against cdk9, histone H3-phospho-Ser10 (H3-pS10), RNA Polymerase II (Pol II), and rabbit IgG were utilized.Back to article page