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Table 1 Nucleotide and amino acid substitutions in the informative sites of genotype I.

From: Genetic diversity of the E Protein of Dengue Type 3 Virus

Nucleotide

Protein

Domains

  

Genotype I

     

Position

Lineage

Lineage II

Position

Lineagen

Type of amino acid Changes

 
    

Sub-Lineage

     

Gene

Codon

I

II

I

II

Protein

I

II

 

I

48

3

G

A

       

135

3

T

C

       

174

3

G

A

      

II

202

1

A

G

  

68

I

V

Conservative

 

219

3

A

G

       

222

3

T

C

       

282

3

T

C

       

342

3

G

A

       

366

3

A

G

       

393

3

A

G

       

441

3

  

T

C

    

I

474

3

T

C

       

506

2

C

T

  

169

A

V

Conservative

 

516

3

T

C

       

537

3

C

T

       

588

3

A

G

      

II

633

3

C

T

       

640

1

T

C

       

645

3

C

T

       

663

3

  

A

G

     

684

3

T

C

       

692

2

G

A

  

231

R

K

Conservative

 

714

3

T

C

       

735

3

  

G

A

     

759

3

A

G

       

777

3

T

C

       

849

3

  

T

C

    

I

909

1

A

G

  

303

T

A

Nonconservative

III

912

3

  

C

T

     

1101

3

T

A

       

1153

1

C

T

       

1172

2

G

A

  

391

R

K

Conservative

 

1269

3

G

A

      

TM

1281

3

G

A

       

1302

3

C

G

       

1317

3

G

A

       

1329

3

  

A

G

     

1380

3

C

T

       

1436

2

C

T

  

479

A

V

Conservative

 

1466

2

T

C

  

489

V

A

Conservative

 
  1. Domain I: 1–156nt (1–52aa); 397–573nt (133–191aa); 835–882nt (279–294aa)
  2. Domain II: 157–396nt (53–132aa); 574–834nt (192–278aa)
  3. Domain III: 883–1176nt (295–392aa)
  4. Domain TM: 1177–1479nt (393–493aa)
  5. nt:are indicated the nucleotide positions
  6. aa::are indicated the amino acid positions