Skip to main content

Table 9 The frequency of variant amino acids in the N-Terminus of Vpr (Residues 1–16)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of subtype B*

1

M

no change

2

E

D (0.4)

3

Q

H (0.4), R (1.8)

4

A

D (0.7), T (0.4), V (1.1)

5

P

L (0.4), S (0.4)

6

E

A (1.1), D (0.4), K (1.1), Q (0.7)

7

D

N (6.2), V (0.4)

8

Q

H (1.1)

9

G

no change

10

P

L (0.4), S (0.7)

11

Q

A (0.7), E (0.4), P (1.8), S (1.8)

12

R

K (0.4)

13

E

I (0.4), Q (1.1), V (0.7)

14

P

Q (0.4), S (0.7)

15

Y

C (0.4), D (0.4), F (6.9), H (5.0), N (0.7), S (0.4), V (0.4)

16

N

A (0.4), H (1.1), I (0.4), Q (0.7), P (0.4), R (0.4), S (0.4), T (0.7)

  1. *275 Vpr alleles were used for analysis.
  2. The numbers in the parentheses represent the percent frequency of the variant amino acid in the Vpr alleles analyzed.