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Table 9 The frequency of variant amino acids in the N-Terminus of Vpr (Residues 1–16)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue Residues in NL4-3 Vpr Variant residue(s) noted in viruses of subtype B*
1 M no change
2 E D (0.4)
3 Q H (0.4), R (1.8)
4 A D (0.7), T (0.4), V (1.1)
5 P L (0.4), S (0.4)
6 E A (1.1), D (0.4), K (1.1), Q (0.7)
7 D N (6.2), V (0.4)
8 Q H (1.1)
9 G no change
10 P L (0.4), S (0.7)
11 Q A (0.7), E (0.4), P (1.8), S (1.8)
12 R K (0.4)
13 E I (0.4), Q (1.1), V (0.7)
14 P Q (0.4), S (0.7)
15 Y C (0.4), D (0.4), F (6.9), H (5.0), N (0.7), S (0.4), V (0.4)
16 N A (0.4), H (1.1), I (0.4), Q (0.7), P (0.4), R (0.4), S (0.4), T (0.7)
  1. *275 Vpr alleles were used for analysis.
  2. The numbers in the parentheses represent the percent frequency of the variant amino acid in the Vpr alleles analyzed.