Table 5 The polymorphisms in Helical Domain II of Vpr (residues 38 – 50)
Residue | Residues in NL4-3 Vpr | Variant residue(s) noted in viruses of different clades | Number of variants |
|---|---|---|---|
38 | W | C, F, T, Y | 4 |
39 | L | F | 1 |
40 | H | I, L, M, N, Q, R, T, Y | 8 |
41 | N | A, D, E, G, H, Q, R, S, W | 9 |
42 | L | C, I, F, M, V | 5 |
43 | G | E, R | 2 |
44 | Q | E, H, L, K, N, R, T, V | 8 |
45 | H | F, L, Q, W, Y | 5 |
46 | I | D, V | 2 |
47 | Y | H | 1 |
48 | E | A, D, G, H, I, K, N, Q, R, S, T, V, Y | 13 |
49 | T | H, N, M, S, Y | 5 |
50 | Y | H, S | 2 |