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Table 20 Effect of variant amino acids on CTL Epitope corresponding to residues 66–74 of Vpr

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Amino Acid Sequence of Predicted Epitope Scoreβ
Prototype sequence (start position 66)α  
QLLFVHFRI 223.888
Natural variations observed at this epitope  
HLLFVHFRI 7.612
KLLFVHFRI 783.608
LLLFVHFRI 380.609
RLLFVHFRI 223.888
QFLFVHFRI 0.155
QILFVHFRI 30.785
QMLFVHFRI 161.697
QPLFVHFRI 1.461
QQLFVHFRI 22.700
QLIFVHFRI 60.510
QLMFVHFRI 223.888
QLPFVHFRI 60.510
QLRFVHFRI 4.599
QLLFVLFRI 514.942
QLLFVYFRI 335.832
QLLFVHLRI 38.601
QLLFVHYRI 38.601
QLLFVHSRI 38.601
QLLFVHFRF 1.599
QLLFVHFRH 1.599
QLLFVHFRL 458.437
QLLFVHFRM 106.613
QLLFVHFRN 1.599
QLLFVHFRS 1.599
QLLFVHFRT 159.920
QLLFVHFRV 1,492.586
  1. α Accession No.: A1.TZ.01.A341_AY253314
  2. β Estimate of Half Time of Disassociation of a Molecule Containing This Epitope