A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Table 17 The predicted HLA Class 1 CTL epitopes in HIV-1 Vpr

Location of the predicted epitope	Amino acid sequence	HLA allele
7 – 15	DQGPQREPY	B62
8 – 16	QGPQREPYN	Dd
11 – 19	QREPYNEWM	B_2705
14 – 22	PYNEWMLDL	A24, Kd
18 – 26	WMLDLLEDL	A_0201, A_0205, B_2705, B_3901, Db_revised, Kd
26 – 34	LKHEAVRHF	Cattle_A20
31 – 39	VRHFPRPWL	B_2705
34 – 42	FPRPWLHEL	B7, Cw_0401
38 – 46	WLHELGQQI	A_0201
39 – 47	LHELGQQIY	B_3801
49 – 57	TYGDTWEGV	Kd
60 – 68	IVRTLQQLL	B7
61 – 69	VRTLQQLLF	B_2702, B_2705
64 – 72	LQQLLFVHF	B62, B_2705, B_3902
65 – 73	QQLLFVHFR	A_3101, B_2705, Cattle_A20
66 – 74	QLLFVHFRI	A_0201
72 – 80	FRIGCQHSR	B_2705, Cattle_A20
79 – 87	SRIGIIRGR	B_2705, Cattle_A20
87 – 95	RRGRNGSGR	B_2705, Cattle_A20

ISSN: 1743-422X