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Table 15 The frequency of variant amino acids in the Carboxy-Terminal Region of Vpr (Residues 78–96)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of subtype B

78

H

L (0.7)

79

S

no change

80

R

A (5.1)

81

I

G (0.4), M (0.7), V (0.4)

82

G

D (0.7), S (0.7)

83

V

I (86.9), L (0.4), T (0.7)

84

T

A (0.4), F (0.4), G (0.7), I (30.9), L (2.5), M (0.4), N (0.7), S (0.4), V (0.4)

85

R

H (0.4), I (0.4), L (2.5), P (15.6), Q (28.4), T (0.4), Y (1.1)

86

Q

M (0.4), P (1.1), R (21.1), S (1.5), V (1.1)

87

R

A (0.4), G (1.5), K (0.4), M (0.4), N (0.4), S (3.3), T (3.6)

88

R

A (2.2), G (1.5), I (0.4), S (0.4), T (0.7)

89

A

E (0.7), G (0.4), P (0.7), R (2.2), S (2.2), T (10.2), V (0.4)

90

R

G (0.4), N (0.4), S (0.4)

91

N

D (1.5), H (0.4), I (0.4), K (0.4)

92

G

A (0.4), E (0.4), R (0.7)

93

A

D (0.4), L (0.4), P (0.7), S (6.5), T (2.2), V (0.4)

94

S

F (0.4), G (2.5), N (1.1), R (3.3), V (0.4)

95

R

A (0.4), D (0.4), I (0.4), K (0.4), T (1.1), S (0.4)

96

S

P (4.0)