Table 14 The frequency of variant amino acids in Helical Domain III of Vpr (Residues 55–77)
Residue | Residues in NL4-3 Vpr | Variant residue(s) noted in viruses of subtype B |
|---|---|---|
55 | A | E (2.2), P (1.1), Q (0.4), T (19.6), V (1.8) |
56 | G | R (0.4), E (0.7) |
57 | V | W (0.4) |
58 | E | G (1.1), I (0.4), K (1.1), Q (0.7), V (0.4) |
59 | A | L (0.4), P (0.4), S (0.4), V (0.4) |
60 | I | L (16.4) |
61 | I | L (0.4), M (1.1), T (3.3), V (1.5) |
62 | R | K (0.7), L (0.4), S (0.4) |
63 | I | M (5.8), S (1.8), T (11.3), V (1.8) |
64 | L | no change |
65 | Q | H (0.4) |
66 | Q | no change |
67 | L | M (1.5), P(0.7) |
68 | L | M (1.5) |
69 | F | L (1.8) |
70 | I | T (2.9), V (1.1) |
71 | H | L (0.4), Y (0.4) |
72 | F | S (1.5), Y (0.4) |
73 | R | T (0.7) |
74 | I | L (0.4), M (0.4), V (0.4) |
75 | G | R (1.1) |
76 | C | G (1.1) |
77 | R | H (5.5), Q (42.5) |