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Table 14 The frequency of variant amino acids in Helical Domain III of Vpr (Residues 55–77)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue Residues in NL4-3 Vpr Variant residue(s) noted in viruses of subtype B
55 A E (2.2), P (1.1), Q (0.4), T (19.6), V (1.8)
56 G R (0.4), E (0.7)
57 V W (0.4)
58 E G (1.1), I (0.4), K (1.1), Q (0.7), V (0.4)
59 A L (0.4), P (0.4), S (0.4), V (0.4)
60 I L (16.4)
61 I L (0.4), M (1.1), T (3.3), V (1.5)
62 R K (0.7), L (0.4), S (0.4)
63 I M (5.8), S (1.8), T (11.3), V (1.8)
64 L no change
65 Q H (0.4)
66 Q no change
67 L M (1.5), P(0.7)
68 L M (1.5)
69 F L (1.8)
70 I T (2.9), V (1.1)
71 H L (0.4), Y (0.4)
72 F S (1.5), Y (0.4)
73 R T (0.7)
74 I L (0.4), M (0.4), V (0.4)
75 G R (1.1)
76 C G (1.1)
77 R H (5.5), Q (42.5)