Skip to main content

Table 12 The frequency of variant amino acids in Helical Domain II of Vpr (Residues 38–50)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue Residues in NL4-3 Vpr Variant residue(s) noted in viruses of subtype B
38 W no change
39 L F (0.4), I (0.4)
40 H L (2.2), N (0.4), Q (1.5), R (0.4), T (0.4), Y (0.4)
41 N A (0.7), D (0.7), E (0.4), G (52.0), S (30.5)
42 L no change
43 G E (0.4), R (0.4)
44 Q R (0.4)
45 H F (0.7), L (1.1), Q (0.4), Y (24.4)
46 I no change
47 Y H (0.4)
48 E A (0.4), D (2.5), G (1.1), K (0.4), Q (0.4), V (0.4)
49 T N (0.7)
50 Y S (0.4)