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Table 12 The frequency of variant amino acids in Helical Domain II of Vpr (Residues 38–50)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of subtype B

38

W

no change

39

L

F (0.4), I (0.4)

40

H

L (2.2), N (0.4), Q (1.5), R (0.4), T (0.4), Y (0.4)

41

N

A (0.7), D (0.7), E (0.4), G (52.0), S (30.5)

42

L

no change

43

G

E (0.4), R (0.4)

44

Q

R (0.4)

45

H

F (0.7), L (1.1), Q (0.4), Y (24.4)

46

I

no change

47

Y

H (0.4)

48

E

A (0.4), D (2.5), G (1.1), K (0.4), Q (0.4), V (0.4)

49

T

N (0.7)

50

Y

S (0.4)