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Table 3 Positions of potential post-translational modification sites

From: Correlating novel variable and conserved motifs in the Hemagglutinin protein with significant biological functions

Motif ID Expression Start
position of
the motif
End
position of
the motif
Years observed
CK2_PHOSPHO_SITE Casein kinase II phosphorylation site. [ST]-x(2)-[DE]. 44 47 1968,1969,1971,1972
   81 84  
   142 145 1972
   203 206  
   416 419  
   432 435  
   456 459  
PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [ST]-x-[RK] 64 66 All years except 1982
   123 125  
   152 154  
   154 156  
   159 161  
   173 175 1972
   190 192 1975
   203 205 1975, 1980, 1982, 1983, 1984, 1985, 1987, 1988, 1989, 1992
   215 217  
   221 223  
   222 224  
   243 245  
   278 280  
   329 331  
   467 469  
   496 498  
cAMP_PHOSPHO_SITE cAMP- and cGMP-dependent protein kinase phosphorylation site. [RK](2)-x-[ST] 156 159 1975, 1980, 1982, 1983, 1984, 1985, 1987, 1988, 1989, 1992, 1999
ASN_GLYCOSYLATION N-glycosylation site N-{P}-[ST]-{P} 24 27 All years except 1971, 1972
   38 41  
   54 57  
   79 82 1975, 1980, 1982, 1983, 1984, 1985, 1987, 1988, 1989, 1992, 1999
   97 100 1968, 1969, 1971, 1972, 1973
   138 141 1999
   142 145 1974, 1980, 1982, 1983, 1984, 1985, 1987, 1988, 1989, 1992, 1999
   149 152 1999
   181 184  
   262 265 1980, 1982, 1983,
1984, 1985, 1987,
1988, 1989, 1992,
1999
   301 304  
   499 502  
MYRISTYL
N-myristylation site
G-{EDRKHPFYW}-
x(2)-[STAGCN]-{P}.
21 26  
   77 82 1968,1969,1971,1972,
1973, 1974, 1975
   145 150 All years except 1972
   150 155 All years except 1989,
1992
   151 156 All years except 1989,
1992, and 1999
   158 163 1975, 1980, 1982,
1983, 1984, 1985,
1987, 1988, 1989,
1992,
   291 296 1974, 1975, 1980,
1982, 1983, 1984,
1985, 1987, 1988,
1989, 1992,
   302 307  
   346 351  
   349 354  
   361 366  
   376 381  
   495 500 1973, 1974, 1975,
1980, 1982, 1983,
1984, 1985, 1987,
1988, 1989, 1992,
   558 563 All years except 1989,
  1. Prosite motifs detected for the H3N2 sequences using PPSearch this includes 24 phosphorylation, 12 glycosylation and 14 myristylation sites. Potential phosphorylation sites include casein kinase II phosphorylation site, protein kinase C phosphorylation site and cAMP- and cGMP-dependent protein kinase phosphorylation site, ASN glycosylation motifs and N-myristylation sites. The start and end positions of each motif are shown, as well as the regular expression of the motif. Unless otherwise indicated, sites have been observed in all 17 consensus sequences.