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Table 1 Vaginal Genotypic Associations in 43 Women

From: A predominance of R5-like HIV genotypes in vaginal secretions is associated with elevated plasma HIV-1 RNA levels and the absence of anti-retroviral therapy

 

R5-like Genotypes

(n = 29)

X4-like Genotypes

(n = 14)

p-value*

High Plasma RNA Levels

≥ 10,000 copies HIV RNA/mL

62.1%

14.3%

0.01

Low Plasma RNA Levels

< 1,000 copies HIV RNA/mL

20.7%

71.4%

0.004

High Vaginal RNA Levels

> 500 copies HIV RNA/sample

48.3%

44.4%

1.00

Low Vaginal RNA Levels

< 100 copies HIV RNA/sample

41.4%

42.9%

0.81

ART Use

38.0%

85.7%

0.01

< 200 CD4+ T lymphocytes/ul

34.6%

44%

0.44#

  1. *Chi Square (Χ2) analyses
  2. #Fisher Exact Test; data from 81% of the cohort available for analysis