Figure 2
From: Identification of new HIV-1 Gag-specific cytotoxic T lymphocyte responses in BALB/c mice
Peptide-specific CD8+ T cell responses against the HIV-1 Gag antigen in mice immunized with Gag or with the combination Gag and Tat. After 3 immunizations, fresh splenocytes were pooled and purified, then CD8+ T cells were tested by IFNγ Elispot assay after stimulation with the indicated 15 mers (panel A), or with the indicated 8–10 mers derived from the above 15 mers (panel B). Results from mice immunized with Gag (empty bars) and from mice immunized with Gag and Tat (filled bars) are expressed as SFU ± SD/106 cells. The mean +/- SD of three independent experiments is shown.