Skip to main content

Advertisement

Table 2 Metastatic nodes in lungs

From: Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

Experimental groups No. of mice in group No. of metastatic nodes in lungs of experimental animalsa
   mouse1 mouse2 mouse3 mouse4 mouse5 mouse6 mouse7 mouse8
PBS 7 3 5 3 18 3 10 1  
OncdSyn 8 2 0 0 0 2 0 0 0
  1. Experimental animals in PBS and OncdSyn groups were sacrificed on day 33 post-inoculation of 4T1 cells and the lungs were removed and examined for metastatic node formation as described in Materials and Methods. aPBS > OncdSyn (Wilcoxon Two-Sample test, p = 0.002).