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Table 1 Metastatic nodes in internal organs

From: Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

Experimental groups

No. of mice in group

No. of mice with metastases in internal organs

No. of mice with metastases in liver

No. of mice with metastases in spleen

No. of mice with metastases in kidney

PBS

9

9

6

7

3

OncSyn

7

4

2

2

0

OncdSyn

7

3

1

2

0

  1. Experimental animals were sacrificed on day 42 post-injection of 4T1 cells and the internal organs were removed and examined for metastases formation by gross pathological evaluation as described in Materials and Methods.
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Virology Journal

ISSN: 1743-422X