Table 4 Mortality of BALB/c Mice Inoculated Intranasally with Wild Type or CDV Resistant Vaccinia Viruses
From: Isolation and characterization of cidofovir resistant vaccinia viruses
Mortality | ||||
|---|---|---|---|---|
Virusa | Number | Percent | MDDb | LD90 |
VV-WR c | ||||
1.6 × 104 | 15/15 | 100 | 8.5 | 4.4 × 103 |
1.6 × 103 | 2/15 | 13 | 8.5 | -- |
1.6 × 102 | 0/15 | 0 | -- | -- |
16 | 0/15 | 0 | -- | -- |
1.6 | 0/15 | 0 | -- | -- |
CDV R 15A c | ||||
Stock, 6 × 104 | 0/15 | 0 | -- | -- |
6 × 103 | 0/15 | 0 | -- | -- |
6 × 102 | 0/15 | 0 | -- | -- |
60 | 0/15 | 0 | -- | -- |
6 | 0/15 | 0 | -- | -- |
CDV R 16A c | ||||
Stock, 8 × 105 | 3/15 | 20 | 8.0 | >8 × 105 |
8 × 103 | 0/15 | 0 | -- | -- |
8 × 102 | 0/15 | 0 | -- | -- |
80 | 0/15 | 0 | -- | -- |
8 | 0/15 | 0 | -- | -- |