Table 1 CDV resistant VV E9L genotype
From: Isolation and characterization of cidofovir resistant vaccinia viruses
Virus | Parental virus strain | Original mutation in E9L | E9L sequence of reconstructed virus |
|---|---|---|---|
CDVR 1 | VV WR | A314V | A314V |
CDVR 2 | VV TK::GFP | A314V | A314V |
CDVR 11 | VV TK::GFP, line 11 | A314V; P738S | ND |
CDVR 14 | VV WR, line 14 | A314V | ND |
CDVR 15 | VV WR, line 15 | M671I | M671I, ΔK174 |
CDVR 16 | VV WR, line 16 | ΔK174 | ΔK174 |