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Figure 3 | Virology Journal

Figure 3

From: The herpesvirus 8 encoded chemokines vCCL2 (vMIP-II) and vCCL3 (vMIP-III) target the human but not the murine lymphotactin receptor

Figure 3

Inhibition of the human and murine lymphotactin receptor by the viral antagonist vCCL2. Dose-response experiments for inhibition of IP3-turnover by the antagonist vCCL2 induced by XCL1 (black square) mXCL1 (black triangle) and vCCL3 (white circle) in COS-7 cells transiently transfected with the human and murine lymphotactin receptors XCR1 and mXCR1 and the promiscuous chimeric G-protein Gqi4myr. All assays were performed in duplicate.

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