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Table 5 The proportion of subjects who seroconverted or cleared serum HBV DNA by age of recruitment and interval after recruitment

From: Changes in viral load and HBsAg and HBeAg status with age in HBV chronic carriers in The Gambia

a) HBsAg seroconversion
Age (yrs) at recruitment Interval after recruitment
  First 5 years 5–9 years 10–19 years
*1–4 18/60 (30%) 1/33 (3.3%) 1/29 (3%)
*5–9 13/62 (21%) 0/27 0/22
10–14 7/23 (30%) 0/4 0/5
15–19 4/15 (27%) 0/0 0/0
b)    
HBeAg seroconversion
Age (yrs) at recruitment First 5 years 5–9 years 10–19 years
*1–4 12/36 (33%) 6/16 (37%) 7/10 (70%)
*5–9 10/29 (34%) 4/12 (33%) 5/7 (71%)
10–14 4/11 (36%) 1/2 (50%) 1/1 (100%)
15–19 1/4 (25%) 0/0 0/0
c)    
Serum HBV DNA clearance
Age (yrs) at recruitment First 5 years 5–9 years 10–19 years
*1–4 8/23 (34.7%) 4/12 (33.3%) 2/16 (12.5%)
*5–9 5/29 (17.2% 3/11 (27.2%) 1/12 (8.3%)
10–14 1/9 (11.1%) 0/2 (0%) 0/4 (0%)
15–19 1/3 (33.3%) 0/0 0/0
  1. *The p-values for the test of trend over time for the first five years after recruitment is < 0.01, < 0.01 and < 0.05 for HBsAg, HBeAg and HBV DNA respectively.