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Table 5 The proportion of subjects who seroconverted or cleared serum HBV DNA by age of recruitment and interval after recruitment

From: Changes in viral load and HBsAg and HBeAg status with age in HBV chronic carriers in The Gambia

a) HBsAg seroconversion

Age (yrs) at recruitment

Interval after recruitment

 

First 5 years

5–9 years

10–19 years

*1–4

18/60 (30%)

1/33 (3.3%)

1/29 (3%)

*5–9

13/62 (21%)

0/27

0/22

10–14

7/23 (30%)

0/4

0/5

15–19

4/15 (27%)

0/0

0/0

b)

   

HBeAg seroconversion

Age (yrs) at recruitment

First 5 years

5–9 years

10–19 years

*1–4

12/36 (33%)

6/16 (37%)

7/10 (70%)

*5–9

10/29 (34%)

4/12 (33%)

5/7 (71%)

10–14

4/11 (36%)

1/2 (50%)

1/1 (100%)

15–19

1/4 (25%)

0/0

0/0

c)

   

Serum HBV DNA clearance

Age (yrs) at recruitment

First 5 years

5–9 years

10–19 years

*1–4

8/23 (34.7%)

4/12 (33.3%)

2/16 (12.5%)

*5–9

5/29 (17.2%

3/11 (27.2%)

1/12 (8.3%)

10–14

1/9 (11.1%)

0/2 (0%)

0/4 (0%)

15–19

1/3 (33.3%)

0/0

0/0

  1. *The p-values for the test of trend over time for the first five years after recruitment is < 0.01, < 0.01 and < 0.05 for HBsAg, HBeAg and HBV DNA respectively.