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Figure 1 | Virology Journal

Figure 1

From: Therapeutic immunisation of rabbits with cottontail rabbit papillomavirus (CRPV) virus-like particles (VLP) induces regression of established papillomas

Figure 1

Regression of papillomas on the backs of rabbits (NZW) following vaccination with CRPV VLPs. A total of nine rabbits were challenged with 10-fold dilutions of infectious CRPV (10-fold dilution two sites per dilution). The rabbits were divided into two groups and immunized 3 times at 2 week intervals (↑) with CRPV VLPs(n = 5), or pControl (n = 4) antigen. The appearance of papillomas was monitored, the papilloma sizes were measured weekly beginning at week seven and the GMDs calculated. The mean GMDs and SEM of papillomas were plotted against time for the sites challenged with 10-2 dilution of infectious CRPV. *P ≤ 0.05 (Mann-Whitney U-test).

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