Figure 2
From: HDAC inhibitors stimulate viral transcription by multiple mechanisms
Effects of HDACi treatment on chromosomes carrying RNA Polymerase II. 30 min, 8 hour and 48 hour SV40 minichromosomes either untreated or treated with 250 μM NaBu or 120 nM TSA were immune selected using 10 μl of antibody against RNAPII. Data is expressed as the percentage of SV40 minichromosomes containing RNA Polymerase II and represent the average of three independent experiments.