Gene | dN/dS |
---|
 | H3N2 | H1N1a |
---|
HA | 0.23 | 0.18 |
HA1 | 0.53 | 0.21 |
HA2 | 0.11 | 0.08 |
NA | 0.25 | 0.17 |
PB2 | 0.06 | Na |
PB1b | 0.07 | Na |
PA | 0.08 | Na |
NP | 0.08 | Na |
M1 | 0.07 | Na |
M2 | 0.38 | Na |
NS1 | 0.23 | Na |
NS2 | 0.19 | Na |
- * dN/dS is the ratio of nonsynonymous vs. synonymous substitutions calculated by SLAC likelihood analysis.
- a The internal genes of H1N1 viruses were not included due to the few sequences available (Na). H3 n = 204, N2 n = 166, internal genes n = 15, H1 n = 27, N1 n = 30.
- b dN/dS for PB1-F2 was not included because the method used was biased by the PB1-F2 +1 reading frame from PB1. Synonymous substitutions in PB1 would therefore be assigned as non-synonymous in PB1-F2 not reflecting positive selection on the PB1-F2 itself.