Constancy and diversity in the flavivirus fusion peptide

Table 2 Wild-type fusion peptide sequences in other flaviviruses

Flavivirus	Vector	Wild-type sequence^a
Additional mosquito-borne not in Table 1^b	Mosquito	DRGWGNGCGLFGKGSI
Viruses with variations only in amino acid 16^c	Mosquito	DRGWGNGCGLFGKGSX
Iguape virus	Mosquito	DRGWN NGCGLFGKGSL
Bussuquara	Mosquito	N RGWN NGCGLFGKGD I
Seabird tick-borne viruses^d	Tick	DRGWGNH CGLFGKGSI
Kadam virus	Tick	DRGWGNN CGLFGKGSI
Some NKV^e	None known	DRGWGNGCGLFGKGSI
Modoc virus	None known	DRGWGNGCA LFGKGSI
Tamana bat virus^f	None known	DRGWDS GCFI FGKGEV
Cell fusing agent (CFAV)	No known vertebrate host	N RGWGT GCFKW GI GFV
CFA Puerto Rico (CFAV)	No known vertebrate host	N RGWGT GCFKW GI GFV
Culex flavivirus (CXFV)	No known vertebrate host	N RGWGT GCFKW GI GFV
Kamiti River virus (KRV)	No known vertebrate host	N RGWGT GCFEW GL GQV

^aChanges from the amino acids in the most common mosquito-borne sequence are in bold.
^bIncluding Usutu, Sepik and Entebbe bat, Ilheus, Bagaza and Yokose viruses
^cKokobera, Rocio, Kédougou and Zika viruses in which amino acid 16, X, = M, L, Y and L respectively
^dTyuleniy, Meaban and Saumarez Reef viruses
^eRio Bravo, Apoi and Montana myotis leukoencephalitis viruses
^fA new genus has been proposed for this virus.

ISSN: 1743-422X