Table 1 Nucleotide and amino acid identity with reference strains, by virus protein
Nucleotide Identity (amino acid identity) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Region | HPeV1a | HPeV2b | HPeV3c | HPeV3d | HPeV4e | HPeV4f | HPeV5g | HPeV5h | HPeV6i | HPeV6j |
5'UTR | 86.6 | 84.9 | 84.9 | 85.2 | 88.9 | 90.8 | ND* | ND | 88.3 | ND |
VP0 | 82.6 (94.1) | 75.7 (84.1) | 70.6 (73.4) | 71.0 (73.4) | 72.9 (78.9) | 72.9 (79.2) | 72.3 (79.2) | 72.3 (79.2) | 72.7 (78.9) | 72.3 (79.2) |
VP3 | 76.9 (89.3) | 72.8 (82.2) | 68.1 (76.3) | 67.9 (76.7) | 71.7 (79.8) | 70.2 (80.2) | 68.9 (76.7) | 68.5 (77.1) | 73.1 (83.4) | 72.1 (83.8) |
VP1 | 76.6 (89.6) | 71.1 (79.2) | 64.2 (70.6) | 64.6 (71.0) | 70.7 (74.0) | 71.7 (77.1) | 69.6 (74.0) | 65.7 (71.4) | 69.7 (74.9) | 69.3 (74.9) |
2A | 76.7 (89.3) | 77.1 (87.3) | 87.1 (88.0) | 88.7 (87.3) | 76.2 (89.3) | 88.2 (94.7) | 79.1 (88.7) | 76.2 (88.7) | 79.8 (88.7) | 78.2 (88.7) |
2B | 82.2 (96.7) | 78.4 (95.9) | 91.5 (100.0) | 91.0 (100.0) | 83.1 (100.0) | 85.2 (100.0) | 83.9 (98.4) | 83.3 (98.4) | 82.0 (97.5) | 82.8 (98.4) |
2C | 79.4 (92.7) | 77.4 (86.6) | 92.8 (99.1) | 92.0 (98.8) | 82.1 (97.3) | 88.1 (98.2) | 81.8 (95.1) | 79.3 (93.9) | 78.6 (91.8) | 80.1 (96.4) |
3A | 75.8 (87.2) | 76.9 (83.8) | 91.2 (91.5) | 92.6 (94.0) | 81.8 (93.2) | 83.2 (92.3) | 80.1 (81.2) | 77.5 (88.9) | 78.6 (88.0) | 80.3 (91.5) |
3B | 71.7 (90.0) | 70.0 (90.0) | 86.7 (85.0) | 86.7 (90.0) | 78.3 (95.0) | 73.3 (85.0) | 80.0 (90.0) | 66.7 (90.0) | 78.3 (90.0) | 76.7 (90.0) |
3C | 81.0 (97.0) | 81.7 (97.0) | 91.0 (98.0) | 91.3 (98.5) | 86.8 (98.0) | 87.0 (97.5) | 79.5 (99.0) | 80.5 (96.0) | 84.2 (98.0) | 81.3 (97.0) |
3D | 82.8 (95.9) | 82.9 (94.2) | 91.0 (97.0) | 90.8 (97.0) | 88.7 (97.0) | 87.9 (97.7) | 82.3 (95.1) | 82.4 (93.8) | 83.9 (95.7) | 82.3 (95.3) |
3'UTR | 83.3 | 87.9 | 94.5 | 92.3 | 89.0 | 94.5 | 84.6 | 89.0 | 83.5 | 84.6 |