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Table 4 Inhibitory efficacy of a type I IFN pre-treatment on Vero/CD150 cells before MV infection

From: Wild type measles virus attenuation independent of type I IFN

  

Concentration of IFN added (IU/mL)

Time before infection

Strain

5000

1000

500

100

0

8 h

G954-PBL

100*

92

95

63

0

 

G954-V13

100

95

89

56

0

 

Ed-Zagreb

100

79

65

58

0

24 h

G954-PBL

100

100

100

95

0

 

G954-V13

100

100

100

67

0

 

Ed-Zagreb

100

100

100

43

0

48 h

G954-PBL

100

100

100

91

0

 

G954-V13

100

100

100

80

0

 

Ed-Zagreb

100

100

100

81

0

  1. * Inhibition indices were calculated as follow: 100 × [1 – (PFU(type I IFN = x)/PFU(type I IFN = 0)]