From: Wild type measles virus attenuation independent of type I IFN
Mice genotype (no. of mice) | Viral strain | Mortality rate (time/days) | MV replication (10 days pi) (*) | anti-N response (15 days pi)(†) | |
---|---|---|---|---|---|
brain | lung | ||||
C57/Bl6 (8) | G954 PBL | 0 % | - | - | - |
G954 V13 | 0 % | - | - | - | |
CD150 tg (6–8) | G954 PBL | 100% (9–15 d) | +++ | + | ++ |
G954 V13 | 0% | - | - | +/++ | |
UV inactivated G954 V13 | 0% | nd | nd | - | |
CD150/IFNARKO (8–10) | G954 PBL | 100% (9–11 d) | nd | nd | nd |
G954 V13 | 0% | nd | nd | +/++ |