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Table 4 Differentially regulated Th genes of HepG2 hepatocytes infected with DENV.

From: Molecular profiling of T-helper immune genes during dengue virus infection

Gene Gene name Fold Change Immune cell activation Inflammatory responses Thrombo-cytopenia Vascular permeability
Th1 immune response       
S152/T14 CD 27 -2.06    
CSF2 GMCSF -2.91
CDw218a/IL-1Rrp Interleukin 18 receptor 1 -3.15     
Tp44 CD28 -7.07    
CD154/CD40L CD40 ligand -9.20
Th2 immune response       
AILIM/CD278 Inducible T-cell co-stimulator 2.28    
CC-CKR-2/CCR2A Chemokine receptor 2 4.08  
CC-CKR-3/CD193 Chemokine receptor 3 4.54    
HP40/IL-9 Interleukin 9 -2.49  
BSF1/IL-4 Interleukin 4 -2.73
EDF/IL-5 Interleukin 5 -7.12   
Th1\Th2 immune response       
PTPRC Protein tyrosine phosphatase, receptor type, C -3.73  
4-1BB/CD137 Tumor necrosis factor receptor superfamily -3.41  
Transcriptional Factors       
STAT4 Signal transducer and activator of transcription 4 -2.17