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Table 3 Differentially regulated Th genes of K562 cells infected with DENV.

From: Molecular profiling of T-helper immune genes during dengue virus infection

Gene Gene name Fold Change Immune cell activation Inflammatory responses Thrombo-cytopenia Vascular permeability
Th1 immune response       
RP11-102M16.1 Interleukin 12 receptor 2.01    
DIF/TNF-alpha Tumor necrosis factor α 2.06    
CC-CKR-5/CCCKR5 Chemokine receptor 5 2.30    
CSF2 GMCSF 2.45
CD80 CD28LG/CD28LG1 2.60    
TLR6 Toll-like receptor 6 6.04
CD69 CLEC2C 14.62
IL2 Interleukin 2 -2.20
APT1LG1/CD178 FASLG -2.48     
CLMF/CLMF2 Interleukin 12B -3.35   
CD121b/IL1RB Interleukin 1 receptor -3.67     
Th2 immune response       
CC-CKR-2/CCR2A Chemokine receptor 2 2.14  
CC-CKR-4/CKR4 Chemokine receptor 4 3.25
CC-CKR-3/CD193 Chemokine receptor 3 4.44    
RANTES Chemokine ligand 5 31.78
BSF1/IL-4 Interleukin 4 -2.25
HDR GATA binding protein 3 -2.61   
IL1RL1LG/Il1rl1l Transmembrane emp24 protein transport domain -2.74     
AILIM/CD278 Inducible T-cell co-stimulator -2.75    
CD124/IL4RA Interleukin 4 receptor -3.52   
FIC/MARC Chemokine ligand 7 -3.76  
Th1\Th2 immune response       
LAT Linker for activation of T cells 4.69    
4-1BB/CD137 Tumor necrosis factor receptor superfamily 4.98  
BSF2/HGF Interleukin 6 6.96
IL-7 Interleukin 7 -2.87  
PTPRC Protein tyrosine phosphatase, receptor type, C -3.39  
Transcriptional Factors       
SOCS2 Suppressor of cytokine signaling 2 2.27    
ZNF163 Growth factor independent 1 -2.01