Table 3 Nonsynonymous mutations found in sequences of LACV RNA that was RT-PCR amplified from field collected mosquitoes
From: Potential for La Crosse virus segment reassortment in nature
Segment | Genome location (nt) | Nucleotide Change | Amino Acid Change |
|---|---|---|---|
L | 252 | C → A | Pro → His |
L | 282 | C → A | Pro → Glu |
L | 313 | G → A | Met → Ile |
L | 321 | T → C | Tyr → Ala |
L | 374 | A → G | Thr → Ala |
L | 489 | A → G | Asp → Gly |
L | 490 | T → C | Arg → Gly |
L | 536 | A → G | Asn → Asp |
L | 547 | T → G | Phe → Cys |
L | 555 | A → G | Lys → Arg |
L | 561 | T → C | Ser → Leu |
L | 576 | T → G | Phe → Cys |
L | 608 | G → A | Ala → Thr |
M | 1663 | A → G | Ile → Met |
M | 1749 | G → A | Asn → Ser |
M | 1754 | T → C | Tyr → His |
M | 1782 | A → G | Asp → Gly |
M | 1815 | T → C | Val → Ala |
M | 1826 | T → C | Ser → Pro |
M | 1866 | A → G | His → Arg |
M | 1881 | T → C | Val → Ala |
M | 1887 | A → G | Asn → Ser |
M | 1898 | T → C | Cys → Arg |
M | 1913 | T → C | Trp → Arg |
M | 1958 | A → G | Thr → Ala |
M | 1961 | A → G | Lys → Glu |
M | 1964 | T → C | Phe → Leu |
S | 209 | T → C | Phe → Ser |
S | 273 | A → C | Lys → Asn |
S | 298 | A → G | Ile → Val |
S | 340 | A → G | Asn → Asp |
S | 347 | A → G | Asp → Gly |
S | 400 | T → C | Tyr → His |
S | 419 | A → T | Glu → Val |
S | 445 | A → G | Thr → Ala |
S | 463 | G → A | Ala → Thr |