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Table 1 Statistical significance of weight loss between infected groups of mice

From: Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in mice

Comparison

Titer

Day

No. mice

P-value

P < 0.05

vΔF2d4rev versus vΔF2

104

5

5

0.0079

Yes

 

105

5

5

0.0079

Yes

 

106

5

5

0.8413

No

vΔF2d4rev versus vd4

104

5

5

0.0079

Yes

 

105

5

5

0.0079

Yes

 

106

5

5

0.6905

No

vΔF2d4rev versus vΔF2d4

104

5

5

0.0317

Yes

 

105

5

5

0.0079

Yes

 

106

5

5

0.0079

Yes

vΔF2d4rev versus vΔF2d4(-FP)

104

5

5

0.0079

Yes

 

105

5

5

0.0079

Yes

 

106

5

5

0.0952

No

vΔF2 versus vd4

104

5

5

0.0952

No

 

105

5

5

0.1508

No

 

106

5

5

0.5476

No

vΔF2 versus vΔF2d4

104

5

5

0.3095

No

 

105

5

5

0.0556

No

 

106

5

5

0.0079

Yes

vΔF2 versus vΔF2d4(-FP)

104

5

5

0.3095

No

 

105

5

5

0.8413

No

 

106

5

5

0.1508

No

vd4 versus vΔF2d4

104

5

5

0.5476

No

 

105

5

5

0.5476

No

 

106

5

5

0.1508

No

vd4 versus vΔF2d4(-FP)

104

5

5

0.1508

No

 

105

5

5

0.0317

Yes

 

106

5

5

0.8413

No

  1. P values of all surviving mice (n = 5) on day 5 at specific viral titers were calculated based on the Mann-Whitney Test (non-parametric, two-tailed, and 95% confidence intervals) with P < 0.05 considered significant.