Figure 5From: Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in miceSerial virus passage in active and quiescent HFF. Quiescent (A) and active (B) HFF were infected with 5 PFU per cell of WR or indicated mutant virus. After 24 h, the cells were harvested and 10% of the lysate used to infect fresh quiescent or active HFF. The procedure was repeated for a total of 7 serial infections. Experiments were carried out in triplicate. Average titers are shown and bars represent the standard error of the mean.Back to article page