Figure 6
From: Adaptation to cell culture induces functional differences in measles virus proteins
Cell culture adaptation affects the inhibition of IFN-γ signaling by the P and V proteins of MeV. Experiments were performed as described in the legend to figure 5, except that a reporter plasmid expressing firefly luciferase under the control of an IFN-γ-responsive promoter and IFN-γ were used for stimulation. (A) results of IFN-γ signaling assays with P proteins from D87-wt and D-CEF, (B) inhibition of IFN-γ signaling by the V proteins. Bars marked with a are significantly different from VC+ with a P ≤ 0.05. (**: P ≤ 0.001)