Figure 1

RSV infection regulates interferon (IFN)-induced gene expression. SPC-A1 cells were infected with RSV at moi 3, and then INF-a was added into culture at the indicated time points at a final concentration of 1000 U/mL for 30 min. Un-infected cells were treated with IFN-a at time 0, and so on. Total cellular RNA was extracted and G1P3 mRNA was quantified by real-time PCR. To examine MG11, total cellular RNA was extracted at the indicated time points after infection. Data are folds increase compared to un-treated SPC-A1cell controls, and shown as means ± SEs of three independent experiments.