Table 1 Differences in number of nucleotide and amino acid compositions, synonymous and nonsynonymous nucleotide substitutions, and predicted antigenic epitopes between sub-clade 2.2.1.-2.2.2. Swedish H5N1 avian influenza viruses.
Gene | Region of comparison/nucleotide/ | Difference between sub-clade 2.2.1.-2.2.2. Swedish viruses | Number of synonymous/nonsynonymous nucleotide changes | Average number of predicted antigenic epitopes | |||
|---|---|---|---|---|---|---|---|
Average number of nucleotide differences | Average number of amino acid differences | 2.2.1. | 2.2.2. | 2.2.1. | 2.2.2. | ||
PB2 | 73–2193 | 23.7 | 4.5 | 0/1 | 6/4 | 32 | 32 |
PB1 | 22–2199 | 20.1 | 6.9 | 6/3 | 10/4 | Nd | Nd |
PB1-F2: 1.1 | 1.1 | 0/0 | 0/1 | ||||
PA | 60–2091 | 13 | 3.2 | 1/0 | 3/2 | 28 | 28 |
HA | 49–1636 | 15.5 | 1.5 | 1/2 | 5/5 | 22.5 | 22 |
NP | 1–1497 | 16.1 | 6.2 | 2/5 | 8/10 | 15 | 15.1 |
NA | 1–1344 | 14.8 | 8.6 | 10/6 | 9/13 | 19.5 | 17.8 |
MP | MP1: 1–950 | 12 | 4.2 | 3/2 | 9/14 | Nd | Nd |
MP2: 1–262 | 5.3 | 2.9 | 0/2 | 4/6 | |||
NS | NS1: 1–678 | 9.3 | 3.7 | 1/1 | 8/14 | ||
NS2: 1–366 | 6.8 | 3.5 | 1/1 | 9/11 | Nd | Nd | |