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Figure 6 | Virology Journal

Figure 6

From: Neuraminidase activity provides a practical read-out for a high throughput influenza antiviral screening assay

Figure 6

Example of an HTS assay. The plate map is shown in the upper panel, with wells set aside for background and virus controls. Each plate also includes known inhibitors, zanamivir and amantadine, at concentrations known to inhibit virus replication. The lower panel shows the results of NA activity for an assay that evaluated the antiviral activity of a panel of ion channel inhibitors. Activity is represented by a range of color; blue representing low relative fluorescence units (RFU), that is, no or little NA activity, and red representing high RFU, that is, a high amount of NA activity.

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