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Figure 2 | Virology Journal

Figure 2

From: Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection

Figure 2

CD8+ cells secreting IFNγ as % of tetramer/pentamer+CD8+ cells. PMC or SMC were isolated from the lungs and the spleens, respectively, of mice on days 8 and 28 after the primary (A, B) or the secondary (C, D) infection, as indicated under the plots. The values were determined by dividing the numbers of IFNγ+CD8+ cells by the numbers of tetramer/pentamer+CD8+ cells and expressed as percentages. RSV and VV-M2-specific CD8+ T cells were analyzed using the RSV-specific tetramer, and the influenza virus-specific CD8+ T cells were analyzed using the influenza virus-specific pentamer. The data are from the experiment shown in Table 1. The values for the lungs and the spleens are shown by black and striped bars, respectively.

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Virology Journal

ISSN: 1743-422X