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Figure 3 | Virology Journal

Figure 3

From: Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector

Figure 3

Hepatocyte cell alterations following infection of HepG2 with VT7-HCV7.9. HepG2 cells uninfected or infected with the recombinant VT7-HCV7.9 in the presence or absence of the inducer IPTG were chemically fixed at 16 h p.i and then processed for conventional embedding in an epoxy resin.A: Cellular architecture of uninfected HepG2 cells. B: A general view of a cell infected with VT7-HCV7.9 in the absence of IPTG, showing the VACV forms IVs and IMVs.C, D and E: A general view of a cell infected with VT7-HCV7.9 in the presence of IPTG, showing large EDS surrounded by vacuoles and the presence of "virus-like particles" surrounded with membranes (*). Note: Vacuole (V) and electron dense structures in membranous webs (EDS). Bar: 200 nm.

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Virology Journal

ISSN: 1743-422X