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Table 2 Consensus sequences of the RdRp for members of the Picornavirales for the domains identified by Koonin & Dolja [17]. Conserved amino acids are highlighted and any conserved amino acid properties.

From: The use of RNA-dependent RNA polymerase for the taxonomic assignment of Picorna-like viruses (order Picornavirales) infecting Apis mellifera L. populations

Virus Family/Genus Domain I Domain II Domain III Domain IV Domain V Domain VI Domain VII Domain VIII
Picornaviridae XXX KD E LRXXX XXXXXXXXXXXXX R XXXXXXXXXXXXXXX X G XXP-XXXXXX XDXXXXDXXXX XGXXPS GXXXTXXXNXXXNXXXXXXXX XXX Y GDD XXX XXXX FLKR X XXXXXXXXXX
Comoviridae EXX KD E XLXXR XFXXLXXXXNXXXRXXFLXXXXXXX-XXR VGXXXXXXEWXX CDYXXFDGXXX XXGIXXGXXLTVXXNSXXNEXLXXXXX XXX Y GDD NLI XXXD FLKR X XXXXXXXXXX
Sadwavirus ACA KD E KTXXR IFEILPFXXNIXXRXYXXFXMQXXM-XXH VGXNVYSXSWDX GDYXGFDTXTP XGGTPS GFAXTVXINSVVNXFYLXWXW XSX Y GDD NXV XEXD FLKR X PLXKXXIEER
Cheravirus DFP KD E KTXXK LFXILPVDYNILVRKYFLSFVSXXM-XXH VGIDXXSNEWSI GDYSRFDGITP TSGIPS GFPLTVIVNSLVNXFFXHFXY YAX Y GDD NLX EKVD FLKR X PLNXVNITER
Sequiviridae ECX KD E RRXLX XFXILXXEXNXXXRXXFXDFXXXVM-XXR VGINPXSXEWSD GDXXXFDGXXX XXGXPS GFXMTVIFNSFXNXXXXXXAW XXX Y GDD NXV XXXX FLKR X PLXKXSIEEX
Dicistroviridae XXL KD XXXXXX X F XXXXXXXXXXXYXXXXXXXXXXX-XXX XGXNXXSXXWXX G D XXXXDXXXX XXXXPS GXXXTXXXNXXXXXXXXXXXX XXX Y GDD XXX XXXXXX KR X PXXXXXXXXX
Iflavirus XXX KD XXXXXX XXXXXPXXXXXXX R XXXXXFXXXXX-XXX XGXXXXXXX W XX X D YXXXXXXXX XXGXXXGXXXTXXXNXXXNXXXXXXXX XXXX GDD XXX XXXXX L XXX XXXXXXXXXX
Marnaviridae ATK KD E ARLIG TFYAASMNVIMAVRKYFCPVLQALK-ANP IGTNAFGKDWAD GDYSSFDMSHN IGWVMS GVPLTAELSSTLNQIYMRVVW LIV Y GDD NNA EDAE FLKR L PLSWDSINKR
Properties    2        2  3  2      2      1        4     4   4         1         55                  413         2  
  1. X: variable position within family/genus
  2. -: deletion
  3. 1: Aliphatic amino acid
  4. 2: Hydrophobic amino acid
  5. 3: Basic amino acid
  6. 4: Aromatic amino acid
  7. 5: Neutral amino acid
  8. Bold type and underline type indicating 100 and > 75% amino acid conservation respectively.