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Table 2 Comparisons of serological markers for HBV replication versus HBVDNA copies in serum specimens.

From: Serum levels of preS antigen (HBpreSAg) in chronic hepatitis B virus infected patients

  HBV DNA+ HBV DNA-   Sensitivity(%) Specificity(%) PPV(%) NPV (%) Overall (%)
HBpreSAg+ 48 34   68 56 59 66 62
HBpreSAg- 23 44 CI,95% 55–78 45–67    
n = 149  
  HBV DNA+ HBV DNA-   Sensitivity(%) Specificity(%) PPV(%) NPV (%) Overall (%)
HBeAg+ 43 7   61 91 86 72 77
HBeAg- 28 71 CI,95% 48–72 82-96    
n=149  
  HBeAg+ HBeAg-   Sensitivity(%) Specificity(%) PPV(%) NPV (%) Overall (%)
HBpreSAg+ 35 49   70 53 42 79 58
HBpreSAg- 15 55 CI,95% 55-82 43-63    
n=154