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Table 2 Comparisons of serological markers for HBV replication versus HBVDNA copies in serum specimens.

From: Serum levels of preS antigen (HBpreSAg) in chronic hepatitis B virus infected patients

 

HBV DNA+

HBV DNA-

 

Sensitivity(%)

Specificity(%)

PPV(%)

NPV (%)

Overall (%)

HBpreSAg+

48

34

 

68

56

59

66

62

HBpreSAg-

23

44

CI,95%

55–78

45–67

   

n = 149

 
 

HBV DNA+

HBV DNA-

 

Sensitivity(%)

Specificity(%)

PPV(%)

NPV (%)

Overall (%)

HBeAg+

43

7

 

61

91

86

72

77

HBeAg-

28

71

CI,95%

48–72

82-96

   

n=149

 
 

HBeAg+

HBeAg-

 

Sensitivity(%)

Specificity(%)

PPV(%)

NPV (%)

Overall (%)

HBpreSAg+

35

49

 

70

53

42

79

58

HBpreSAg-

15

55

CI,95%

55-82

43-63

   

n=154

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