Figure 2From: Dengue virus serotype infection specifies the activation of the unfolded protein responseDengue infection induces phosphorylation of eIF2α. (A) A549 cells were infected with DENV1 or DENV2 viruses at 10 MOI and lysed at indicated time points in lysis buffer. Protein extracts were subjected to immunoblot analysis with anti-phosphoserine51-eIF2α (top panel), and anti-eIF2α (bottom panel) antibodies. (B) Phosphoserine51-eIF2α levels from (A) were quantified and normalized to eIF2α levels and plotted.Back to article page