Figure 6
From: Role of CD151, A tetraspanin, in porcine reproductive and respiratory syndrome virus infection
Effect of siRNA against CD151 on PRRSV infection. (A) To examine the effect of siRNA against CD151 on PRRSV infection, siRNA was transfected into MARC-145 cells. The suppression of the cell surface expression of CD151 by the transfection of siRNA was shown by flow cytometric analysis for the untransfected MARC-145 cells (A1) and the transfected MARC-145 cells (A2). An isotype-matched control is represented by the dotted lines. (B) The effect of siRNA on PRRSV infection was shown by immunofluorescence antibody assay using FITC-conjugated SDOW-17, a MAb against PRRSV nucleocapsid protein for the untransfected MARC-145 cells (B 1) and the transfected MARC-145 cells (B 2).