Figure 2From: HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome systemRole of DCAF1 in Vpr-induced G2 arrest. A. Identification of Vpr-interacting proteins by affinity chromatography followed by mass spectrometry; band labeled as "c" was identified as being DCAF1. B. Knockdown of DCAF1 abolishes Vpr function. C. Western blot demonstrates efficient knockdown of DCAF1. NS, non-specific siRNA.Back to article page